Multiplex immunofluorescence (mIF) allows investigators to capture expression patterns of several markers in a single tissue section. Composite images integrate signals from up to 6 markers in a single 'stacked' picture.
The lab conducts automated mIF slide staining, acquires multispectral slide images, and uses advanced machine learning-based image analysis algorithms for cell segmentation and characterization.
Measure up to 6 tissue antigens simultaneously, plus a DAPI stain for DNA.
Use cell lineage markers to characterize heterogeneous tissues.
Spatially resolve patterns of marker co-expression or activation of cell signaling pathways in tissues.